Estradiol, levonorgestrel moderate indinavir decreases the metabolism of oral contraceptives and non-oral combination contraceptives, the auc for ethinyl estradiol and norethindrone increased by 24 -17 and 26 -14 , respectively, when coadministered with indinavir.
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2Other kidney concerns Because indinavir can affect your kidneysyou may wish to be cautious about using other medications which have the potential to cause kidney damageThe following list of drugswhich is not exhaustivecan cause kidney dysfunction or damage:
When HIV becomes resistant to one drug in a classit sometimes becomes resistant to other drugs in that classThis is called cross-resistanceFeel free to talk with your doctor about your current and future treatment optionsTo help you decide what these future therapies might beat some point your doctor can have a small sample of your blood analysed using resistance testingShould HIV in your body become resistant to indinavir your doctorwith the help of resistance testingcan help put together a new treatment regimen for you.
Dieleman JPvan Rossum AMStricker BCet alPersistent leukocyturia and loss of renal function in a prospectively monitored cohort of HIV-infected patients treated with indinavirJournal of Acquired Immune Deficiency Syndromes 2003;32(2135-142.
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